So far, the TEDDY Network has produced more than 50 publications, that vary widely in focus and theme.
The TEDDY publication policy is an important evidence of the Network’s commitment in the field of paediatric high-level scientific information.
TEDDY members have still continued to work together to favour awareness on the topics of paediatric research and to spread information on the rational use of paediatric medicines to identify unmet medical needs in paediatrics.
TEDDY Network Publications
2021
Sultana J, Crisafulli S, Almas M, Antonazzo I, Baan E, Bartolini C, Bertuccio MP, Bonifazi F, Capuano A, Didio A, Ehrenstein V, Felisi MG, Ferrajolo C, Fontana A, Francisca R, Fourrier-Reglat A, Fortuny J, Gini R, Hyeraci G, Hoeve C, Kontogiorgis C, Isgrò V, Lalagkas PN, L’Abbate L, Layton D, Landi A, Narduzzi S, Roque Pereira L, Poulentzas G, Rafaniello C, Roberto G, Scondotto G, Sportiello L, Toma M, Toussi M, Verhamme K, Volpe E, Trifirò G
Overview of the EU PAS register post-authorization studies performed in Europe from September 2010 to December 2018
Pharmacoepidemiol Drug Saf 2022 Jan 29. doi: 10.1002/pds.5413. Online ahead of print
2020
Aurich B, Vermeulen E, Elie V, Driessens MHE, Kubiak C, Bonifazi D, Jacqz-Aigrain E.
Informed consent for neonatal trials: practical points to consider and a check list.
BMJ Paediatrics Open. 29 December 2020; doi: 10.1136/bmjpo-2020-000847
Altavilla A, Giannuzzi A, Lupo M, Bonifazi D, Ceci A. Ethical, Legal and Regulatory Issues of Paediatric Translational Research. Call for an Adequate Model of Governance. European Journal of Health Law. May 2020. 1–19. Available at: https://brill.com/view/journals/ejhl/27/3/article-p213_3.xml
Gini R, Sturkenboom MC, Sultana J, Cave A, Landi A, Pacurariu A, Roberto G, Schink T, Candore G, Slattery J, Trifirò G; Working Group 3 of ENCePP. Different strategies to execute multi‐database studies for medicines surveillance in real world setting: a reflection on the European model. Clin Pharmacol Ther. 2020 Apr 3. doi: 10.1002/cpt.1833
2019
Ruggieri L, Bonifazi D, Landi A, Bonifazi F, Bartoloni F, Costello M, Grazia Felisi M, Gasthuys E, Godo A, Martinon Torres F, Nadal D, Nuytinik L, Rocchi F, Turner M, Ceci A. Survey by TEDDY – European Network of Excellence for Paediatric Clinical Research demonstrates potential for Europe-wide trials. Acta Paediatr. 2019 Sep 18. doi: 10.1111/apa.15020. [Epub ahead of print] PubMed PMID: 31532836. Available at: https://onlinelibrary.wiley.com/doi/abs/10.1111/apa.15020
Bueno-Campaña M, Sainz T, Alba M, Del Rosal T, Mendez-Echevarría A, Echevarria R, Tagarro A, Ruperez-Lucas M, Herrreros ML, Latorre L, Calvo C. Lung ultrasound for prediction of respiratory support in infants with acute bronchiolitis: A cohort study. Pediatr Pulmonol. 2019 Jun;54(6):873-880. doi: 10.1002/ppul.24287. Epub 2019 Mar 5. PubMed PMID: 30838805. Available at: https://onlinelibrary.wiley.com/doi/abs/10.1002/ppul.24287
Martín Del Valle F, Menasalvas Ruiz A, Cilla A, González AV, de Ceano Vivas M, Cabrerizo Sanz M, Calvo C. Neurodevelopment medium-term outcome after parechovirus infection. Early Hum Dev. 2019 May; 132:1-5. Doi:10.1016/j.earlhumdev.2019.03.005. Epub 2019 Mar 22. PubMed PMID: 30908988. Available at: https://www.sciencedirect.com/science/article/abs/pii/S0378378218306522?via%3Dihub
Calvo C, Millan C, Romero MP, Méndez-Echevarría A. Could human bocavirus be a causative agent of parotitis in children? Enferm Infecc Microbiol Clin. 2019 Mar;37(3):207-208. doi: 10.1016/j.eimc.2018.04.001. Epub 2018 May 8. English, Spanish. PubMed PMID: 29751940. Available at: https://www.sciencedirect.com/science/article/pii/S0213005X18301691?via%3Dihub
Intini A., Bonifazi D, Migliaccio G. Challenges and New Frontiers in the Paediatric Drug Discovery and Development (Book chapter). Drug Discovery and Development – New Advances. 2019 Apr 8. Publisher: IntechOpen. DOI: http://dx.doi.org/10.5772/intechopen.85635. Available at: https://www.intechopen.com/online-first/challenges-and-new-frontiers-in-the-paediatric-drug-discovery-and-development
Benavides-Nieto M, Méndez-Echevarría A, Del Rosal T, García-García ML, Casas I, Pozo F, de la Serna O, Lopez-Granados E, Rodriguez-Pena R, Calvo C. The role of respiratory viruses in children with humoral immunodeficiency on immunoglobulin replacement therapy. Pediatr Pulmonol. 2019 Feb;54(2):194-199. doi: 10.1002/ppul.24214. Epub 2018 Dec 21. PubMed PMID: 30575324. Available at: https://onlinelibrary.wiley.com/doi/abs/10.1002/ppul.24214
2018
Lupo M, Intini A, Filannino D. Informed Participation and Patient Empowerment: A Patient-Centered Approach to Improve Pediatric Clinical Research. The Management of Clinical Trials, 978-1-78923-239-4; Publisher: Intech, June, 6th 2018. Available at: https://www.intechopen.com/books/the-management-of-clinical-trials/informed-participation-and-patient-empowerment-a-patient-centered-approach-to-improve-pediatric-clin
Chiaruttini G, Felisi M and Bonifazi D. Challenges in Paediatric Clinical Trials: How to Make It Feasible. The Management of Clinical Trials, 978-1-78923-239-4; Publisher: Intech, June, 6th 2018. Available at: https://www.intechopen.com/books/the-management-of-clinical-trials/challenges-in-paediatric-clinical-trials-how-to-make-it-feasible
Alcobendas R, Remesal A, Murias S, Nuñez E, Calvo C. Outpatients with acute osteoarticular infections had favourable outcomes when they received just oral antibiotics without intravenous antibiotics. Acta Paediatr. 2018 Apr 29. doi: 10.1111/apa.14373. [Epub ahead of print] PMID: 29705992. Available at: https://onlinelibrary.wiley.com/doi/abs/10.1111/apa.14373
Martín Del Valle F, Calvo C, Martinez-Rienda I, Cilla A, Romero MP, Menasalvas AI, Reis-Iglesias L, Roda D, Pena MJ, Rabella N, Portugués de la Red MDM, Megías G, Moreno-Docón A, Otero A, Cabrerizo M; Grupo de Estudio de las infecciones por enterovirus y parechovirus en niños. Epidemiological and clinical characteristics of infants admitted to hospital due to human parechovirus infections: A prospective study in Spain. An Pediatr (Barc). 2018 Feb;88(2):82-88. doi: 10.1016/j.anpedi.2017.02.009. Epub 2017 Mar 30. Spanish. PMID: 28365283. Available at: https://www.ncbi.nlm.nih.gov/pubmed/28365283
Mellado Peña MJ, Santiago García B, Baquero-Artigao F, Moreno Pérez D, Piñeiro Pérez R, Méndez Echevarría A, Ramos Amador JT, Gómez-Pastrana Durán D, Noguera Julian A; Grupo de Trabajo de Tuberculosis e Infección por otras Micobacterias de la Sociedad Española de Infectología Pediátrica. [Tuberculosis treatment for children: An update]. An Pediatr (Barc). 2018 Jan;88(1): 52.e1-52.e12. doi: 10.1016/j.anpedi.2017.05.013. Epub 2017 Jul 18. Spanish. PubMed PMID: 28729186. Available at: https://www.analesdepediatria.org/en-tuberculosis-treatment-for-children-an-articulo-S2341287917302041
2017
Garcia-Garcia ML, Calvo C, Ruiz S, Pozo F, Del Pozo V, Remedios L, Exposito N, Tellez A, Casas I. Role of viral coinfections in asthma development. PLoS One. 2017 Dec 5;12(12):e0189083. doi: 10.1371/journal.pone.0189083. eCollection 2017. PMID: 29206851. Available at: https://www.ncbi.nlm.nih.gov/pubmed/29206851
Veal GJ, Malik S, Lupo M, MacFarlane S, Lepola P, Costello M, Ceci A, Boué C, Lecour C, Otto A, Rastegari M, Berry P. Investigating the roles and training of paediatric research nurses working across Europe: a questionnaire-based survey.BMJ Paediatr Open. 2017 Sep 5;1(1):e000170. doi: 10.1136/bmjpo-2017-000170.eCollection2017. http://bmjpaedsopen.bmj.com/content/1/1/e000170
García-García ML, Calvo C, Moreira A, Cañas JA, Pozo F, Sastre B, Quevedo S, Casas I, del Pozo V. Thymic Stromal Lymphopoietin, IL-33 and periostin in hospitalized infants with viral bronchiolitis. Medicine (Baltimore). 2017 May;96(18):e6787. Available at: https://www.ncbi.nlm.nih.gov/pubmed/28471975
Giannuzzi V, Devlieger H, Margari L, Odlind VL, Ragab L, Bellettato CM, D’Avanzo F, Lampe C, Cassis L, Cortès-Saladelafont E, Cazorla ÁG, Barić I, Cvitanović-Šojat L, Fumić K, Dali CI, Bartoloni F, Bonifazi F, Scarpa M, Ceci A. The ethical framework for performing research with rare inherited neurometabolic disease patients. European Journal of Pediatrics. 2017 Mar; 176(3):395-405. Epub 2017 Jan 16. https://link.springer.com/article/10.1007%2Fs00431-017-2852-9
Garcìa ML, Calvo C, Rey C, Dìaz B, Molinero M, Pozo F, Casas I (2017). Human metapnuemovirus infections in hospitalized children and comparison with other respiratory viruses. 2005-2014 prospective study. PLoS ONE 12(3): e0173504. https://doi.org/10.1371/journal. pone.0173504
2016
Paola D’andria, Viviana Giannuzzi, Fedele Bonifazi, Adriana Ceci, Nunzio Denora, Cosimo D. Altomare. Formulating medicines for children: challenges and issues. DOI: http://dx.medra.org/10.17374/CI.2016.98.3.4
2015
Ceci A, Giannuzzi V, Bonifazi D, Felisi M, Bonifazi F and Ruggieri L Clinical Trials in Paediatrics — Regulatory and Methodological Aspects. Drug Discovery and Development – From Molecules to Medicine, Prof. Omboon Vallisuta (Ed.), ISBN: 978-953-51-2128-2, InTech, DOI: 10.5772/60611. Available at: http://www.intechopen.com/books/drug-discovery-and- development-from-molecules-to-medicine/clinical-trials-in-paediatrics- regulatory-and-methodological-aspects
Giannuzzi V, Altavilla A, Ruggieri L, Ceci A. Clinical Trial Application in Europe: What Will Change with the New Regulation? Sci Eng Ethics. 2015 Jun 3. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/26037896
Ruggieri L, Giannuzzi V, Baiardi P, Bonifazi F, Davies EH, Giaquinto C, Bonifazi D, Felisi M, Chiron C, Pressler R, Rabe H, Whitaker MJ, Neubert A, Jacqz-Aigrain E, Eichler I, Turner MA, Ceci A; GRiP Consortium. Successful private-public funding of paediatric medicines research: lessons from the EU programme to fund research into off-patent medicines. Eur J Pediatr. 2015 Apr;174(4):481-91. doi: 10.1007/s00431-014-2398-z. Epub 2014 Sep 23
https://link.springer.com/article/10.1007%2Fs00431-014-2398-z
2014
Piñeiro Péreza R, Ruiz Antoránb MB, Avendaño Solá C, Román Riechmann E, Cabrera García L, Cilleruelo Ortega ML, Mellado Peña MJ. Conocimiento sobre el uso de fármacos off-label en Pediatría. Resultados de una encuesta pediátrica nacional 2012-2013 (estudio OL-PED). An Pediatr (Barc). 2014; 81(1):16-21. Avalaible at: http://www.analesdepediatria.org/es/conocimiento-sobre-el-uso- farmacos/articulo/S1695403313004086/
Piñeiro Pérez R, Martínez Fernández-Llamazares C, Calvo Rey C, Piñeiro Pérez AP, Criado Vega EA, Bravo Acuña J, Cabrera García L, Mellado Peña MJ Asociación Española de Pediatría, Pediamécum: un año de experiencia. An Pediatr (Barc). 2014;81(4):257.e1-257.e6. Available at: http://analesdepediatria.org/es/pediamecum-un-ano- experiencia/articulo/S1695403314001015/
2011
Russo R, Capasso M, Paolucci P, Iolascon A, TEDDY European Network of Excellence. Pediatric pharmacogenetic and pharmacogenomic studies: the current state and future perspectives. Eur J Clin Pharmacol. 2011 May;67 Suppl 1:17-27. doi: 10.1007/s00228-010-0931-1. Epub 2010 Nov 11. https://pubmed.ncbi.nlm.nih.gov/21069522/
Scarpa M, Ceci A, Tomanin R, Mincarone P, Begley D. Personalised medicine in paediatrics: Individualising treatment in children with rare neurological diseases. EPMA Journal (2011) 2:231–239. doi: 10.1007/s13167-011 00812. Epub 2011 May 1.https://pubmed.ncbi.nlm.nih.gov/23199151/